Malignant Melanoma | Borka Association for Cancer
Malignant melanoma is a type of cancer that arises from melanocytes, cells that are found in the skin and are responsible for producing the pigment melanin. Malignant Melanoma subsidesports occurs when melanocytes no longer respond subsidesports to normal cellular mechanisms of cell growth and become able to invade subsidesports locally and to expand to other organs in the body (metastasis), where again invade and disrupt the functions of these organs. subsidesports
Description Melanocytes, produce brown pigment subsidesports known as melanin and are responsible for megjurasnite variations of color and the color of bemkite. Malignant degeneration of melanocytes turn into cancer known as melanoma, in which four different subtypes: the surface spreading melanoma, subsidesports nodular with spreading, lentigo maligna melanoma and akralen lentiginozen. Malignant melanoma can develop anywhere on the body. In men, it is usually the trunk. In women the most common on the back and legs. Subtype of malignancy can affect where the tumor will grow; lentigo melanoma is more common on the face while akralniot lentiginozen melanoma is more common on the palms, soles and nails. Because vertical growth characterizes malignancy, nodular variant of melanoma has the worst prognosis. Fortunately, surface spreading subsidesports is the most common type. Primary tumor begins in the skin, usually of melanocytes to an existing mole. Once you become invasive, can progress beyond subsidesports the point of origin in regional lymph nodes or to travel to other organ systems of the body and get a systemic nature. Untreated, malignant melanoma has a classic progress. Starts and grown locally, penetrating vertically, are distributed by the regional lymph nodes, known as regional metastases. Then you can spread from lymph nodes or the bloodstream blood vessels, thereby allowing the spread of cancer throughout the body. When you develop systemic disease or distant metastases occur, subsidesports melanoma usually occurs in the lungs, brain, liver or bone sometimes. subsidesports Malignancy causing death when his uncontrolled subsidesports growth will disrupt the function of vital organs.
Statistics of new cases of cancer, malignant melanoma is present in 5% of malignancies in men and 4% in women, and also represent the six most common cancer in men and the seventh most common cancer in women. Malignant melanoma is the reason for the incidence of 1.5% of the total number of deaths caused by cancer. The incidence subsidesports of cutaneous malignant melanoma has been steadily increasing, possibly due to greater sun exposure. Currently, the risk of developing the disease is 13 cases per 100 000 population. It affects all age groups but is most frequent in patients between 30 and 60 years of age. Exposure to the sun definitely increases the risk of developing melanoma. However, it is not the only reason for the phenomenon, here is the history of sunburn (especially if severe or early age). Based on this data, the population living in areas with high sun exposure is subject to increased risk. Malignant melanoma can occur on skin anywhere on the body. It is estimated that 50% to 70% spontaneously develop the rest starts from an existing mole.
Causes and symptoms predisposing causes for the development of malignant melanoma are usually environmental and genetic causes. Environmental factors occur after excessive sun exposure. There are also genetic and familial syndromes. Equally, and ultraviolet radiation, and damage from oxygen free radicals caused by exposure to the sun can damage cells, especially their DNA. It is believed that this damage is involved in causing mutations that result in the development of malignant melanoma. Positive family history of one or two first-degree relatives who have had melanoma increases the risk of this malignancy based genetic basis. This familial tendency was observed in 8% to 12% of patients. There is a syndrome known as dysplastic (atypical) naevus syndrome characterized by atypical moles with certain clinical characteristics in children under 10 years of age. Such individuals should be monitored closely related to the development of malignant melanoma. The number of moles increases the risk, but it is necessary to consider the size of bemkite. If there are ten large moles than 1 cm have a higher risk than those with a larger number (50-99) smaller moles. When a child is born with a large, congenital moles, careful observation of the change due to the increased risk. Changes that are important in her birth mark are: Asymmetry Border irregularity Color her birth mark Diameter greater than 6 mm
Three of the criteria relating to the variability of the lesion (fear
Malignant melanoma is a type of cancer that arises from melanocytes, cells that are found in the skin and are responsible for producing the pigment melanin. Malignant Melanoma subsidesports occurs when melanocytes no longer respond subsidesports to normal cellular mechanisms of cell growth and become able to invade subsidesports locally and to expand to other organs in the body (metastasis), where again invade and disrupt the functions of these organs. subsidesports
Description Melanocytes, produce brown pigment subsidesports known as melanin and are responsible for megjurasnite variations of color and the color of bemkite. Malignant degeneration of melanocytes turn into cancer known as melanoma, in which four different subtypes: the surface spreading melanoma, subsidesports nodular with spreading, lentigo maligna melanoma and akralen lentiginozen. Malignant melanoma can develop anywhere on the body. In men, it is usually the trunk. In women the most common on the back and legs. Subtype of malignancy can affect where the tumor will grow; lentigo melanoma is more common on the face while akralniot lentiginozen melanoma is more common on the palms, soles and nails. Because vertical growth characterizes malignancy, nodular variant of melanoma has the worst prognosis. Fortunately, surface spreading subsidesports is the most common type. Primary tumor begins in the skin, usually of melanocytes to an existing mole. Once you become invasive, can progress beyond subsidesports the point of origin in regional lymph nodes or to travel to other organ systems of the body and get a systemic nature. Untreated, malignant melanoma has a classic progress. Starts and grown locally, penetrating vertically, are distributed by the regional lymph nodes, known as regional metastases. Then you can spread from lymph nodes or the bloodstream blood vessels, thereby allowing the spread of cancer throughout the body. When you develop systemic disease or distant metastases occur, subsidesports melanoma usually occurs in the lungs, brain, liver or bone sometimes. subsidesports Malignancy causing death when his uncontrolled subsidesports growth will disrupt the function of vital organs.
Statistics of new cases of cancer, malignant melanoma is present in 5% of malignancies in men and 4% in women, and also represent the six most common cancer in men and the seventh most common cancer in women. Malignant melanoma is the reason for the incidence of 1.5% of the total number of deaths caused by cancer. The incidence subsidesports of cutaneous malignant melanoma has been steadily increasing, possibly due to greater sun exposure. Currently, the risk of developing the disease is 13 cases per 100 000 population. It affects all age groups but is most frequent in patients between 30 and 60 years of age. Exposure to the sun definitely increases the risk of developing melanoma. However, it is not the only reason for the phenomenon, here is the history of sunburn (especially if severe or early age). Based on this data, the population living in areas with high sun exposure is subject to increased risk. Malignant melanoma can occur on skin anywhere on the body. It is estimated that 50% to 70% spontaneously develop the rest starts from an existing mole.
Causes and symptoms predisposing causes for the development of malignant melanoma are usually environmental and genetic causes. Environmental factors occur after excessive sun exposure. There are also genetic and familial syndromes. Equally, and ultraviolet radiation, and damage from oxygen free radicals caused by exposure to the sun can damage cells, especially their DNA. It is believed that this damage is involved in causing mutations that result in the development of malignant melanoma. Positive family history of one or two first-degree relatives who have had melanoma increases the risk of this malignancy based genetic basis. This familial tendency was observed in 8% to 12% of patients. There is a syndrome known as dysplastic (atypical) naevus syndrome characterized by atypical moles with certain clinical characteristics in children under 10 years of age. Such individuals should be monitored closely related to the development of malignant melanoma. The number of moles increases the risk, but it is necessary to consider the size of bemkite. If there are ten large moles than 1 cm have a higher risk than those with a larger number (50-99) smaller moles. When a child is born with a large, congenital moles, careful observation of the change due to the increased risk. Changes that are important in her birth mark are: Asymmetry Border irregularity Color her birth mark Diameter greater than 6 mm
Three of the criteria relating to the variability of the lesion (fear
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