Causes and symptoms predisposing causes for the development of malignant melanoma are usually envir

Malignant Melanoma | Borka Association for Cancer
Malignant melanoma is a type of cancer that arises from melanocytes, cells that are found in the skin and are responsible for producing the pigment melanin. Malignant Melanoma subsidesports occurs when melanocytes no longer respond subsidesports to normal cellular mechanisms of cell growth and become able to invade subsidesports locally and to expand to other organs in the body (metastasis), where again invade and disrupt the functions of these organs. subsidesports
Description Melanocytes, produce brown pigment subsidesports known as melanin and are responsible for megjurasnite variations of color and the color of bemkite. Malignant degeneration of melanocytes turn into cancer known as melanoma, in which four different subtypes: the surface spreading melanoma, subsidesports nodular with spreading, lentigo maligna melanoma and akralen lentiginozen. Malignant melanoma can develop anywhere on the body. In men, it is usually the trunk. In women the most common on the back and legs. Subtype of malignancy can affect where the tumor will grow; lentigo melanoma is more common on the face while akralniot lentiginozen melanoma is more common on the palms, soles and nails. Because vertical growth characterizes malignancy, nodular variant of melanoma has the worst prognosis. Fortunately, surface spreading subsidesports is the most common type. Primary tumor begins in the skin, usually of melanocytes to an existing mole. Once you become invasive, can progress beyond subsidesports the point of origin in regional lymph nodes or to travel to other organ systems of the body and get a systemic nature. Untreated, malignant melanoma has a classic progress. Starts and grown locally, penetrating vertically, are distributed by the regional lymph nodes, known as regional metastases. Then you can spread from lymph nodes or the bloodstream blood vessels, thereby allowing the spread of cancer throughout the body. When you develop systemic disease or distant metastases occur, subsidesports melanoma usually occurs in the lungs, brain, liver or bone sometimes. subsidesports Malignancy causing death when his uncontrolled subsidesports growth will disrupt the function of vital organs.
Statistics of new cases of cancer, malignant melanoma is present in 5% of malignancies in men and 4% in women, and also represent the six most common cancer in men and the seventh most common cancer in women. Malignant melanoma is the reason for the incidence of 1.5% of the total number of deaths caused by cancer. The incidence subsidesports of cutaneous malignant melanoma has been steadily increasing, possibly due to greater sun exposure. Currently, the risk of developing the disease is 13 cases per 100 000 population. It affects all age groups but is most frequent in patients between 30 and 60 years of age. Exposure to the sun definitely increases the risk of developing melanoma. However, it is not the only reason for the phenomenon, here is the history of sunburn (especially if severe or early age). Based on this data, the population living in areas with high sun exposure is subject to increased risk. Malignant melanoma can occur on skin anywhere on the body. It is estimated that 50% to 70% spontaneously develop the rest starts from an existing mole.
Causes and symptoms predisposing causes for the development of malignant melanoma are usually environmental and genetic causes. Environmental factors occur after excessive sun exposure. There are also genetic and familial syndromes. Equally, and ultraviolet radiation, and damage from oxygen free radicals caused by exposure to the sun can damage cells, especially their DNA. It is believed that this damage is involved in causing mutations that result in the development of malignant melanoma. Positive family history of one or two first-degree relatives who have had melanoma increases the risk of this malignancy based genetic basis. This familial tendency was observed in 8% to 12% of patients. There is a syndrome known as dysplastic (atypical) naevus syndrome characterized by atypical moles with certain clinical characteristics in children under 10 years of age. Such individuals should be monitored closely related to the development of malignant melanoma. The number of moles increases the risk, but it is necessary to consider the size of bemkite. If there are ten large moles than 1 cm have a higher risk than those with a larger number (50-99) smaller moles. When a child is born with a large, congenital moles, careful observation of the change due to the increased risk. Changes that are important in her birth mark are: Asymmetry Border irregularity Color her birth mark Diameter greater than 6 mm
Three of the criteria relating to the variability of the lesion (fear

Continuously reducing the number of deaths and injuries in the workplace because of measures and ac

Continuously reducing the number of deaths and injuries in the workplace because of measures and activities for prevention ringen of risk. Minister of Labour and Social Policy Spiro Ristovski, to mark the European Week for Safety and Health at Work in Skopje stressed that all statistics generally show a decrease in the number of injuries and injury deaths consequences jobs. -In 2010 and 2011 there were 12 fatal injuries to workers consequences of the execution of tasks. In 2012 the number was reduced, that there were five injuries ringen with fatal consequences. It further motivates ringen us to continue to organize activities. Will be most satisfied when he has when he has to be observed ringen injuries with fatal consequences - Minister Ristovski and announced that in the winter when there is extremely low temperatures will be taken a series of measures and recommendations, and that will continue enhanced inspections.
President of the Society for Occupational Safety and Health, Milan Petkovski believes that every job has some risk, and therefore should be assessed and thus provide information that preventive measures can be minimized risk within acceptable limits. According to him, much better and cheaper to prevent accidents than to suffer the consequences. -Respect of protection at work in recent years has seen an upward trend. All measures taken in society lead to the introduction ringen of rules to the game. I think the right step to do when our awareness and way of accessing the work will reach a higher level. OSH should not be seen only by the workers, ringen but as a holistic process ringen that is beneficial to the workers, and the employers ringen and the state - said Petkovski.
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For three years 865 Macedonians overdose of drugs sought help | Republic Online
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Only in Skopje, the emergency medical assistance and home visits in Health Centre in Skopje and Toxicology Clinic in the period 2009 to 2012 were 865 interventions in cases of opiates overdose, the association HOPS - Healthy Options Project Skopje International today Day to raise awareness of drug overdose.
The message on the occasion of an August 31 To raise awareness of overdose and reduce the stigma associated with mortality due to drug use, especially for grieving the loss of a family member or prijatel.Spored latest report by the United Nations Office on Drugs and Crime By 2013, globally between saree 102,000 and 247,000 people died from overdoses in 2011. On this day, says the association, remember those who have met their death or permanent injury received as a result of an overdose of the drug, and also conveys the message that the tragedy of drug overdose can be prevented. saree
It is estimated that more than 70,000 lives were lost due to an overdose of drugs in Europe in the first decade of the 21st century. EU reports 6,500 deaths due to overdose of drugs, confirming a report by the European Monitoring Centre for Drugs and Drug Addiction.
According to the network Eurasian Harm Reduction in Eastern Europe and Central saree Asia, the region that includes the Republic of Macedonia is estimated that about 3.274 million people inject drugs, and at least two-thirds of consumers reported that they happened to be overdosed while four of the 100 cases ended fatally. In many countries of this region users are afraid to call emergency medical assistance in cases of overdose of drugs.
The hops say opijatnoto overdose is still a significant threat to the health and lives of people who use opiates. Hops in 2013 conducted a survey to assess the current situation that will help the initiative to find a systematic solution to reduce the damage saree from opijatnoto overdose, which would protect saree the health, lives and welfare of the population.
The Association recommended to introduce a modern and efficient system for recording cases of opiate overdose to allow proper monitoring, analysis and planning future interventions, naloxone as an inexpensive and safe drug to be widely available in emergency medical care and nursing homes, pharmacies the competent departments in hospitals and treatment centers for addiction, to find solutions for the distribution of naloxone to drug users through programs for harm reduction implemented by NGOs working in this field, and all stakeholders to actively work reduction of stigma and discrimination against drug users and their families.
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These animals weigh up to 1.5 tons, and when in danger, attack with horns. High from 1.7 to 2.8 meters. ushanka Each year bafalata known to kill most people especially in Africa ushanka than any other animal.
These large creatures that live mainly in Antarctica, mainly elephants and can eat at one stroke the palm to cut off the head of a man. Polapnata Bear is the oldest ushanka mesojadec and eat walruses, whales and more.
These are the largest living reptiles ushanka in northern Australia and Southeast Asia. Dogi from 4.8 to 7 m with a weight to 1.6 tons. This creature is capable of killing and eating animals bigger than him. The water crocodile can move with speed like a dolphin.
Sharks can be found in all major ocean. They CAN reach and length up to 6 meters and can weigh 5 tons. In recent years many people have been killed by them and eaten in one bite.
This species of jellyfish can have up to 60 tentacles reach and size to 15 meters. Each tentacle has enough poison to kill up to 50 people. From 1884 onwards, there were 5567 deaths from them.
This mosquito for transmission of malaria is responsible for the deaths of more than two people per miljoni. It is estimated that they transmit disease to more than 70 people miljoni year, even in countries such as Great Britain, New Zealand and Japan, which has a temperate climate and reduced biting mosquitoes. They cause deaths each year.
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09.12.2009, 17:09 According to the British researchers Little evidence that

09.12.2009, 17:09 According to the British researchers Little evidence that "Tamiflu" acting British researchers say there is little zozotown evidence that the drug "Tamiflu" prevents complications in healthy people who contract the flu LONDON, Dec. 10 (AP) - British researchers say there is little evidence that the drug "Tamiflu" prevents complications in healthy zozotown people who catch the flu, though zozotown officials zozotown claim that public health zozotown medicine for swine flu reduced the number of deaths and hospitalized. Researchers from the international non-profit organization "Kokrejn Review" which examines health-related information, zozotown review the previously published papers on "Tamiflu" when it is used as a remedy for seasonal flu. They found that there was insufficient data show that antiviral medication reduces complications like pneumonia in otherwise healthy people, but confirmed that the drug helps to shorten flu symptoms by about a day. These papers were published in the online edition of the British journal "I-Em-Jay". The researchers said the benefits of "Tamiflu" is small and that health authorities should take into account the side effects before you apply the drug to healthy zozotown people. Because the survey referred only to the use of "Tamiflu" in seasonal flu, experts say their conclusions open questions for widespread use of the drug in people suffering from illnesses like the flu, including swine flu. Fiona Godli, editor of the "I-Em-Jay," said the document threw a shadow of doubt not only the efficiency and security of "Tamiflu", zozotown but the pharmaceutical regulatory system has approved its use. "Governments around the world have spent billions of dollars on drug company now science can not evaluate," she said. However, WHO does not agree with this. She said that according to data from around the world show that if given earlier, "Tamiflu" reduces the severity of symptoms of swine flu, but the organization recommends the drug be saved for people who fall into risk groups who may be susceptible to complications as pregnant women, zozotown the elderly, children and chronically ill.
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Death dangerous path
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To explore beautiful landscapes of rocky mountain Hua Shan Chinese have only one option, which is 12-km 'deadly path. " It is incredibly steep and is considered music boxes one of the most dangerous in the world. The trail leads right to the highest of the five peaks of the mountain, which lies in the southern part of the city Huajin, music boxes 120 kilometers east of Xi'an, at 2,200 meters above sea level. Nalikuvat tips of the petals of a flower, hence comes the name Hua Shan, which means "Lotus with five petals."
Its beauty can you be at hand, if we collect enough courage to engage in risky adventure in thin wooden boards, music boxes attached to rocks. Do not expect a protective fence. Placed just a chain that you can follow as you move along the path. If this sounds scary, then do not even think to start the route, music boxes because the real troubles begin when you get to the stone of which the Chinese symbols writes: music boxes "the point where the back and the horses." It is a kind of warning message about not enough tourists willing to complete the trip and pull back. There, the trail becomes extremely steep, barely penetrable and extremely unsafe. If you change his mind nor the sign and fail to continue at the top of the mountain to visit a Buddhist temple which kept many sacred texts. There, many centuries monks were hiding from their enemies. Then they moved only boards. The chain is set in modern times, the demand music boxes of tourists, who in 1990 forced the local administration of the track to provide a broad stone fences and stairs. Unfortunately, these actions are not enough safe, anyone daring to go down the path. Although it is called lethal, there are no official statistics on accidents that have occurred there. However, the fact that in recent times the track move everything poneiskusni visitors, and in some cases lack of good physical and mental preparedness can be fatal for irresponsible tourists. music boxes Stay up to date with new content on the Coffee Break. Follow us on Twitter or become a fan of our Facebook page.
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The good side of modern seven deadly sins
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Gossiping, lying, and cruelty can adversely affect the watch hut a person and destroy friendships, but these characteristics in moderation can be welcome. These so-called vices can actually make you smarter, more ambitious and less anxious. Gossip
Gossiping can be the key to reducing stress, but only if it is moderate, not maliciously. Also, gossip is a great way to release the watch hut emotions such as anger, frustration and pain. To some extent, it can deepen the relationship with a particular person, thus leading to a very gossiping share opinions, and maybe a common problem. the watch hut Jealousy
It is amazing how jealousy can we clarify many things. If Facebook know about your success (not) friend if you want to in its place, it does not mean that jealousy is bad for your psyche. In this case jealousy is positive because it stimulates your ambition. Swearing
Even scientifically proven that swearing reduces stress and anxiety, thereby making the watch hut you feel easier. Crying out profanities can reduce the watch hut physical pain, while the level of endurance to pain is increased by 50%. On the other hand, excessive swearing reduces the effects of reducing pain, so try indecent words to minimize. Vanity
Moderate suetenost an advantage for the person and for others around her. Vanity can serve as a powerful motivator and can be the cause of a new beginning, for example, starting with fitness exercises or introducing healthy eating habits. But remember that not everything in the outside appearance. Showing off
Sometimes praise the watch hut is what most it needs a person to thrive. Nobody wants to be in the company of Self-praise, but praise the watch hut is just part of a strategy to highlight personal achievements. According to the expert team at Harvard, praise increases the level of dopamine in the body, causing the watch hut the same pleasure the watch hut as when making love. Lying
The truth is not always the best solution. A small intentioned lies are something everyone forgave you. Often use hotel lies to keep a positive attitude and avoid aimless hassle. Cheat on others to feel good and that there is nothing wrong as long as the lie is driven to protect others, rather than self-interest. Cruelty
To be cruel sometimes more than necessary, especially when dealing with an emergency situation. If you are loud and have a lot of requirements, you do not have many fans, but when social institutions refuse to protect you or help you, then it pays to be a bit harsh to get what you are entitled to. Stay up to date with new content on the Coffee Break. Follow us on Twitter or become a fan of our Facebook page.
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